Lead in PDB 4qw2: Fmrp N-Terminal Domain (R138Q)

The structure of Fmrp N-Terminal Domain (R138Q), PDB code: 4qw2 was solved by L.K.Myrick, H.Hashimoto, X.Cheng, S.T.Warren, with X-Ray Crystallography technique. A brief refinement statistics is given in the table below:

Resolution Low / High (Å)	24.90 / 2.99
Space group	P 41 21 2
Cell size a, b, c (Å), α, β, γ (°)	89.087, 89.087, 121.991, 90.00, 90.00, 90.00
R / Rfree (%)	22.7 / 28.3

The binding sites of Lead atom in the Fmrp N-Terminal Domain (R138Q) (pdb code 4qw2). This binding sites where shown within 5.0 Angstroms radius around Lead atom.
In total only one binding site of Lead was determined in the Fmrp N-Terminal Domain (R138Q), PDB code: 4qw2:

Lead binding site 1 out of 1 in the Fmrp N-Terminal Domain (R138Q)


Mono view


Stereo pair view

A full contact list of Lead with other atoms in the Pb binding site number 1 of Fmrp N-Terminal Domain (R138Q) within 5.0Å range: probe atom residue distance (Å) B Occ B:Pb301 b:94.5 occ:0.50 SG B:CYS99 2.4 50.6 1.0 CB B:CYS99 3.8 74.6 1.0 CE1 B:TYR96 4.3 60.0 1.0 CD1 B:TYR96 4.5 51.9 1.0 OG B:SER69 4.6 69.4 1.0 CZ B:TYR96 4.6 56.9 1.0 CA B:CYS99 4.7 76.4 1.0 CH2 B:TRP80 4.8 42.0 1.0 CZ3 B:TRP80 4.9 48.6 1.0 O B:ARG70 4.9 76.4 1.0 CZ2 B:TRP80 4.9 46.9 1.0 O B:CYS99 4.9 79.0 1.0 CG B:TYR96 5.0 49.1 1.0

L.K.Myrick, H.Hashimoto, X.Cheng, S.T.Warren. Human Fmrp Contains An Integral Tandem Agenet (Tudor) and Kh Motif in the Amino Terminal Domain Hum.Mol.Genet. 2014.
ISSN: ESSN 1460-2083
DOI: 10.1093/HMG/DDU586