Lead in PDB 4pc1: Elongation Factor Tu:Ts Complex with A Bound Phosphate

The structure of Elongation Factor Tu:Ts Complex with A Bound Phosphate, PDB code: 4pc1 was solved by S.S.Thirup, with X-Ray Crystallography technique. A brief refinement statistics is given in the table below:

Resolution Low / High (Å)	68.79 / 1.95
Space group	P 21 21 21
Cell size a, b, c (Å), α, β, γ (°)	73.510, 109.770, 195.030, 90.00, 90.00, 90.00
R / Rfree (%)	17.4 / 20.8

The binding sites of Lead atom in the Elongation Factor Tu:Ts Complex with A Bound Phosphate (pdb code 4pc1). This binding sites where shown within 5.0 Angstroms radius around Lead atom.
In total 2 binding sites of Lead where determined in the Elongation Factor Tu:Ts Complex with A Bound Phosphate, PDB code: 4pc1:
Jump to Lead binding site number: 1; 2;

Lead binding site 1 out of 2 in the Elongation Factor Tu:Ts Complex with A Bound Phosphate


Mono view


Stereo pair view

A full contact list of Lead with other atoms in the Pb binding site number 1 of Elongation Factor Tu:Ts Complex with A Bound Phosphate within 5.0Å range: probe atom residue distance (Å) B Occ C:Pb301 b:27.4 occ:0.43 O C:HOH749 2.6 56.0 1.0 O C:HOH667 2.6 34.3 1.0 OE2 D:GLU188 2.7 49.5 1.0 OD2 C:ASP199 2.8 30.7 1.0 OD1 C:ASP199 2.9 27.8 1.0 OE1 D:GLU188 3.0 50.9 1.0 CG C:ASP199 3.2 27.4 1.0 CD D:GLU188 3.2 50.2 1.0 HZ1 D:LYS192 3.6 41.4 1.0 O C:HOH402 3.8 38.9 1.0 HZ3 D:LYS192 4.2 41.4 1.0 NZ D:LYS192 4.3 34.5 1.0 O C:HOH413 4.5 35.8 1.0 HZ2 D:LYS192 4.6 41.4 1.0 O D:HOH461 4.7 50.9 1.0 CB C:ASP199 4.7 23.6 1.0 CG D:GLU188 4.8 45.4 1.0 HB3 C:ASP199 5.0 28.3 1.0

Lead binding site 2 out of 2 in the Elongation Factor Tu:Ts Complex with A Bound Phosphate


Mono view


Stereo pair view

A full contact list of Lead with other atoms in the Pb binding site number 2 of Elongation Factor Tu:Ts Complex with A Bound Phosphate within 5.0Å range: probe atom residue distance (Å) B Occ C:Pb302 b:29.4 occ:0.35 OE2 C:GLU188 2.8 52.3 1.0 OD1 D:ASP199 3.0 29.6 1.0 OE1 C:GLU188 3.1 52.9 1.0 HZ1 C:LYS192 3.2 53.6 1.0 O D:HOH664 3.2 46.3 1.0 OD2 D:ASP199 3.2 31.4 1.0 CD C:GLU188 3.4 50.8 1.0 CG D:ASP199 3.4 29.1 1.0 NZ C:LYS192 4.0 44.7 1.0 HZ3 C:LYS192 4.0 53.6 1.0 HZ2 C:LYS192 4.3 53.6 1.0 O D:HOH710 4.7 47.7 1.0 O D:HOH472 4.7 40.2 1.0 O C:HOH446 4.7 49.0 1.0 CB D:ASP199 4.8 25.2 1.0 HB3 D:ASP199 4.8 30.2 1.0 CG C:GLU188 4.9 48.2 1.0

S.S.Thirup, L.B.Van, T.K.Nielsen, C.R.Knudsen. Structural Outline of the Detailed Mechanism For Elongation Factor Ts Mediated Nucleotide Exchange on Elongation Factor Tu To Be Published.