Lead in PDB 3t8y: Crystal Structure of the Response Regulator Domain of Thermotoga Maritima Cheb

All present enzymatic activity of Crystal Structure of the Response Regulator Domain of Thermotoga Maritima Cheb:
3.1.1.61;

The structure of Crystal Structure of the Response Regulator Domain of Thermotoga Maritima Cheb, PDB code: 3t8y was solved by S.Y.Park, B.R.Crane, with X-Ray Crystallography technique. A brief refinement statistics is given in the table below:

Resolution Low / High (Å)	30.00 / 1.90
Space group	P 21 21 21
Cell size a, b, c (Å), α, β, γ (°)	53.715, 53.679, 131.565, 90.00, 90.00, 90.00
R / Rfree (%)	22.9 / 24.5

The binding sites of Lead atom in the Crystal Structure of the Response Regulator Domain of Thermotoga Maritima Cheb (pdb code 3t8y). This binding sites where shown within 5.0 Angstroms radius around Lead atom.
In total 2 binding sites of Lead where determined in the Crystal Structure of the Response Regulator Domain of Thermotoga Maritima Cheb, PDB code: 3t8y:
Jump to Lead binding site number: 1; 2;

Lead binding site 1 out of 2 in the Crystal Structure of the Response Regulator Domain of Thermotoga Maritima Cheb


Mono view


Stereo pair view

A full contact list of Lead with other atoms in the Pb binding site number 1 of Crystal Structure of the Response Regulator Domain of Thermotoga Maritima Cheb within 5.0Å range: probe atom residue distance (Å) B Occ A:Pb145 b:36.0 occ:0.83 OD2 A:ASP58 2.4 20.3 1.0 OD1 A:ASP13 2.5 35.1 1.0 O A:GLU60 2.6 33.6 1.0 OD1 A:ASP58 2.8 22.0 1.0 CG A:ASP58 3.0 23.9 1.0 CG A:ASP13 3.2 31.7 1.0 OD2 A:ASP13 3.3 35.4 1.0 O A:HOH1004 3.7 20.4 1.0 C A:GLU60 3.8 32.5 1.0 O A:HOH1090 4.1 29.2 1.0 OD1 A:ASP12 4.4 24.4 1.0 CB A:GLU60 4.4 42.5 1.0 OG A:SER113 4.4 44.7 1.0 CA A:GLU60 4.4 35.2 1.0 N A:GLU60 4.4 30.0 1.0 CB A:SER113 4.5 45.1 1.0 NZ A:LYS109 4.5 22.4 1.0 CB A:ASP58 4.5 22.5 1.0 CB A:ASP13 4.5 30.3 1.0 N A:ASP13 4.6 26.3 1.0 CG A:MET61 4.6 28.1 1.0 OD2 A:ASP12 4.8 24.2 1.0 CG A:ASP12 4.8 24.4 1.0 N A:MET61 4.9 31.7 1.0

Lead binding site 2 out of 2 in the Crystal Structure of the Response Regulator Domain of Thermotoga Maritima Cheb


Mono view


Stereo pair view

A full contact list of Lead with other atoms in the Pb binding site number 2 of Crystal Structure of the Response Regulator Domain of Thermotoga Maritima Cheb within 5.0Å range: probe atom residue distance (Å) B Occ B:Pb145 b:32.5 occ:0.81 OD2 B:ASP58 2.5 33.3 1.0 OD1 B:ASP13 2.5 33.5 1.0 O B:GLU60 2.5 34.4 1.0 O B:HOH1073 2.7 34.5 1.0 OD1 B:ASP58 2.7 22.0 1.0 CG B:ASP58 2.9 25.9 1.0 CG B:ASP13 3.3 33.1 1.0 OD2 B:ASP13 3.6 35.1 1.0 O B:HOH1000 3.6 19.9 1.0 C B:GLU60 3.7 31.8 1.0 O B:HOH1065 3.9 33.6 1.0 OD1 B:ASP12 4.2 23.4 1.0 CA B:GLU60 4.3 33.7 1.0 OG B:SER113 4.3 37.7 1.0 CB B:GLU60 4.3 40.3 1.0 N B:GLU60 4.4 24.9 1.0 CB B:SER113 4.4 38.6 1.0 CB B:ASP58 4.4 20.0 1.0 NZ B:LYS109 4.4 25.2 1.0 CB B:ASP13 4.5 31.0 1.0 N B:ASP13 4.6 25.6 1.0 CG B:ASP12 4.7 22.5 1.0 OD2 B:ASP12 4.7 17.9 1.0 N B:MET61 4.8 32.0 1.0 CG B:GLU60 5.0 52.3 1.0

S.Y.Park, B.R.Crane. Structural Insight Into the Low Affinity Between Thermotoga Maritima Chea and Cheb Compared to Their Escherichia Coli/Salmonella Typhimurium Counterparts Int.J.Biol.Macromol. V. 49 794 2011.
ISSN: ISSN 0141-8130
PubMed: 21816169
DOI: 10.1016/J.IJBIOMAC.2011.07.012