Lead in PDB 2oq1: Tandem SH2 Domains of Zap-70 with 19-Mer ZETA1 Peptide

All present enzymatic activity of Tandem SH2 Domains of Zap-70 with 19-Mer ZETA1 Peptide:
2.7.10.2;

The structure of Tandem SH2 Domains of Zap-70 with 19-Mer ZETA1 Peptide, PDB code: 2oq1 was solved by M.H.Hatada, E.R.Laird, J.Green, J.Morgenstern, M.K.Ram, with X-Ray Crystallography technique. A brief refinement statistics is given in the table below:

Resolution Low / High (Å)	10.00 / 1.90
Space group	P 1 21 1
Cell size a, b, c (Å), α, β, γ (°)	50.110, 63.370, 54.000, 90.00, 114.44, 90.00
R / Rfree (%)	20.9 / 25.5

The binding sites of Lead atom in the Tandem SH2 Domains of Zap-70 with 19-Mer ZETA1 Peptide (pdb code 2oq1). This binding sites where shown within 5.0 Angstroms radius around Lead atom.
In total only one binding site of Lead was determined in the Tandem SH2 Domains of Zap-70 with 19-Mer ZETA1 Peptide, PDB code: 2oq1:

Lead binding site 1 out of 1 in the Tandem SH2 Domains of Zap-70 with 19-Mer ZETA1 Peptide


Mono view


Stereo pair view

A full contact list of Lead with other atoms in the Pb binding site number 1 of Tandem SH2 Domains of Zap-70 with 19-Mer ZETA1 Peptide within 5.0Å range: probe atom residue distance (Å) B Occ A:Pb1119 b:28.7 occ:1.00 SG A:CYS119 2.6 24.4 1.0 CB A:CYS119 3.3 16.1 1.0 CA A:CYS119 4.8 15.6 1.0

M.H.Hatada, X.Lu, E.R.Laird, J.Green, J.P.Morgenstern, M.Lou, C.Marr, T.B.Phillips, M.K.Ram, K.Theriault. Molecular Basis For the Interaction of Zap-70 with the T-Cell Receptor Nature V. 377 32 1995.
ISSN: ISSN 0028-0836
PubMed: 7659156
DOI: 10.1038/377032A0