Lead in the structure of Crystal Structure of Zebrafish Ape (pdb 2o3c)

The binding sites of Lead atom in the structure of Crystal Structure of Zebrafish Ape (pdb code 2o3c). This binding sites where shown with 5.0 Angstroms radius around Lead atom. The 2o3c structure was solved by M.M.GEORGIADIS, R.K.GAUR, S.DELAPLANE, J.SVENSON, with X-Ray Crystallography technique, brief refinement statistics is given in the table below: Resolution (A) 50.0-2.3 Space group P1211 a (A) 54.660 b (A) 117.780 c (A) 85.840 alpha (°) 90.00 beta (°) 98.34 gamma (°) 90.00 Rfactor (%) 19.9 Rfree (%) 23.6 Lead Binding Sites: Lead binding site 1 out of 3 in 2o3c Click to enlarge Click to enlarge Mono- and Stereo- picture of 5.0 Angstrom coordination sphere 1 of Lead in the PDB 2o3c. Coordination sphere was calculated for all residues within 5.0 Angstroms distance from the central Lead atom, shown by VdW sphere Residues shown as a stick model or VDW spheres: A: Val62, A: Asp63, A: Gly64, A: Ala67, A: Trp68, A: Lys71, A: Tyr261, A: Gly298, A: Hoh438, A: Hoh453, A: Hoh495, A: Hoh504, conact list: Atom Atom Distance (A) Pb O A:Val62 3.98 Pb C A:Val62 4.95 Pb O A:Asp63 2.20 Pb CB A:Asp63 3.74 Pb OD2 A:Asp63 4.23 Pb C A:Asp63 3.39 Pb OD1 A:Asp63 2.72 Pb CG A:Asp63 3.35 Pb CA A:Asp63 4.20 Pb O A:Gly64 4.17 Pb N A:Gly64 4.39 Pb C A:Gly64 4.81 Pb CA A:Gly64 4.51 Pb C A:Ala67 4.90 Pb CB A:Ala67 3.39 Pb CA A:Ala67 4.69 Pb N A:Trp68 4.71 Pb CE A:Lys71 4.48 Pb NZ A:Lys71 3.89 Pb OH A:Tyr261 4.21 Pb O A:Gly298 4.83 Pb O A:Hoh438 2.62 Pb O A:Hoh453 2.48 Pb O A:Hoh495 4.89 Pb O A:Hoh504 3.76 interactive model: Lead binding site 2 out of 3 in 2o3c Click to enlarge Click to enlarge Mono- and Stereo- picture of 5.0 Angstrom coordination sphere 2 of Lead in the PDB 2o3c. Coordination sphere was calculated for all residues within 5.0 Angstroms distance from the central Lead atom, shown by VdW sphere Residues shown as a stick model or VDW spheres: B: Asp63, B: Glu89, B: Lys91, B: Asp300, B: Hoh443, B: Hoh473, B: Hoh514, conact list: Atom Atom Distance (A) Pb CB B:Asp63 4.61 Pb OD2 B:Asp63 2.60 Pb OD1 B:Asp63 4.54 Pb CG B:Asp63 3.75 Pb OE1 B:Glu89 3.07 Pb OE2 B:Glu89 3.37 Pb CD B:Glu89 3.62 Pb NZ B:Lys91 4.34 Pb OD2 B:Asp300 4.57 Pb O B:Hoh443 3.56 Pb O B:Hoh473 2.63 Pb O B:Hoh514 2.85 interactive model: Lead binding site 3 out of 3 in 2o3c Click to enlarge Click to enlarge Mono- and Stereo- picture of 5.0 Angstrom coordination sphere 3 of Lead in the PDB 2o3c. Coordination sphere was calculated for all residues within 5.0 Angstroms distance from the central Lead atom, shown by VdW sphere Residues shown as a stick model or VDW spheres: C: Asn61, C: Asp63, C: Glu89, C: Lys91, C: Asp300, C: Hoh424, C: Hoh433, C: Hoh454, C: Hoh464, conact list: Atom Atom Distance (A) Pb OD1 C:Asn61 4.94 Pb CB C:Asp63 3.93 Pb OD2 C:Asp63 2.41 Pb C C:Asp63 4.80 Pb OD1 C:Asp63 4.11 Pb CG C:Asp63 3.28 Pb CA C:Asp63 4.03 Pb OE1 C:Glu89 2.28 Pb OE2 C:Glu89 3.53 Pb CD C:Glu89 3.25 Pb CG C:Glu89 4.61 Pb NZ C:Lys91 3.73 Pb OD2 C:Asp300 4.19 Pb OD1 C:Asp300 4.48 Pb CG C:Asp300 4.74 Pb O C:Hoh424 2.46 Pb O C:Hoh433 4.30 Pb O C:Hoh454 2.49 Pb O C:Hoh464 2.36 interactive model: