Lead in PDB 1tn1: Crystallographic and Biochemical Investigation of the Lead(II)- Catalyzed Hydrolysis of Yeast Phenylalanine Trna

The structure of Crystallographic and Biochemical Investigation of the Lead(II)- Catalyzed Hydrolysis of Yeast Phenylalanine Trna, PDB code: 1tn1 was solved by J.C.Dewan, R.S.Brown, B.E.Hingerty, A.Klug, with X-Ray Crystallography technique. A brief refinement statistics is given in the table below:

Resolution Low / High (Å)	N/A / 3.00
Space group	P 1 21 1
Cell size a, b, c (Å), α, β, γ (°)	56.700, 33.200, 63.000, 90.00, 89.90, 90.00
R / Rfree (%)	22.7 / n/a

The structure of Crystallographic and Biochemical Investigation of the Lead(II)- Catalyzed Hydrolysis of Yeast Phenylalanine Trna also contains other interesting chemical elements:

Magnesium

(Mg)

5 atoms

The binding sites of Lead atom in the Crystallographic and Biochemical Investigation of the Lead(II)- Catalyzed Hydrolysis of Yeast Phenylalanine Trna (pdb code 1tn1). This binding sites where shown within 5.0 Angstroms radius around Lead atom.
In total 3 binding sites of Lead where determined in the Crystallographic and Biochemical Investigation of the Lead(II)- Catalyzed Hydrolysis of Yeast Phenylalanine Trna, PDB code: 1tn1:
Jump to Lead binding site number: 1; 2; 3;

Lead binding site 1 out of 3 in the Crystallographic and Biochemical Investigation of the Lead(II)- Catalyzed Hydrolysis of Yeast Phenylalanine Trna


Mono view


Stereo pair view

A full contact list of Lead with other atoms in the Pb binding site number 1 of Crystallographic and Biochemical Investigation of the Lead(II)- Catalyzed Hydrolysis of Yeast Phenylalanine Trna within 5.0Å range: probe atom residue distance (Å) B Occ A:Pb83 b:0.0 occ:1.00 O4 A:U59 2.4 7.8 1.0 MG A:MG80 2.5 20.0 1.0 N3 A:C60 2.9 9.8 1.0 OP1 A:G19 3.3 3.1 1.0 C4 A:U59 3.4 7.8 1.0 O2 A:C60 3.6 9.8 1.0 N4 A:C60 3.7 9.8 1.0 C2 A:C60 3.7 9.8 1.0 C4 A:C60 3.8 9.8 1.0 N3 A:U59 3.8 7.8 1.0 O6 A:G20 4.4 3.8 1.0 C5 A:U59 4.5 7.8 1.0 OP2 A:H2U16 4.7 29.7 1.0 O4' A:H2U16 4.8 29.7 1.0 O A:HOH102 4.8 20.0 1.0 P A:G19 4.8 3.1 1.0

Lead binding site 2 out of 3 in the Crystallographic and Biochemical Investigation of the Lead(II)- Catalyzed Hydrolysis of Yeast Phenylalanine Trna


Mono view


Stereo pair view

A full contact list of Lead with other atoms in the Pb binding site number 2 of Crystallographic and Biochemical Investigation of the Lead(II)- Catalyzed Hydrolysis of Yeast Phenylalanine Trna within 5.0Å range: probe atom residue distance (Å) B Occ A:Pb84 b:0.0 occ:1.00 O A:HOH182 0.8 20.0 1.0 N10 A:SPM77 1.5 46.0 1.0 O A:HOH190 1.6 20.0 1.0 O A:HOH181 1.6 20.0 1.0 C8 A:SPM77 2.0 46.0 1.0 C11 A:SPM77 2.1 46.0 1.0 C9 A:SPM77 2.2 46.0 1.0 O6 A:G45 2.6 5.5 1.0 C12 A:SPM77 3.1 46.0 1.0 C7 A:SPM77 3.4 46.0 1.0 C6 A:G45 3.6 5.5 1.0 N7 A:G45 3.7 5.5 1.0 C5 A:G45 4.0 5.5 1.0 OP2 A:A44 4.2 6.8 1.0 C6 A:SPM77 4.2 46.0 1.0 C13 A:SPM77 4.3 46.0 1.0 N1 A:G45 4.7 5.5 1.0 N1 A:A9 4.8 3.6 1.0 N7 A:A44 4.8 9.0 1.0 OP2 A:A23 4.9 4.6 1.0

Lead binding site 3 out of 3 in the Crystallographic and Biochemical Investigation of the Lead(II)- Catalyzed Hydrolysis of Yeast Phenylalanine Trna


Mono view


Stereo pair view

A full contact list of Lead with other atoms in the Pb binding site number 3 of Crystallographic and Biochemical Investigation of the Lead(II)- Catalyzed Hydrolysis of Yeast Phenylalanine Trna within 5.0Å range: probe atom residue distance (Å) B Occ A:Pb85 b:0.0 occ:1.00 N7 A:YG37 2.5 33.5 1.0 O2 A:OMC32 2.9 27.1 1.0 N7 A:A36 3.0 9.3 1.0 O6 A:YG37 3.3 33.5 1.0 C8 A:YG37 3.5 33.5 1.0 N6 A:A36 3.5 9.3 1.0 C5 A:YG37 3.5 33.5 1.0 O2 A:U33 3.6 40.4 1.0 C5 A:A36 3.7 9.3 1.0 C2 A:OMC32 3.8 27.1 1.0 C6 A:YG37 3.9 33.5 1.0 N3 A:OMC32 3.9 27.1 1.0 C6 A:A36 4.0 9.3 1.0 C8 A:A36 4.0 9.3 1.0 N6 A:A38 4.3 27.3 1.0 C2 A:U33 4.3 40.4 1.0 N7 A:A38 4.4 27.3 1.0 N9 A:YG37 4.7 33.5 1.0 C4 A:YG37 4.7 33.5 1.0 C4 A:A36 4.8 9.3 1.0 N3 A:U33 4.9 40.4 1.0 C6 A:A38 4.9 27.3 1.0 C5 A:A38 5.0 27.3 1.0 N9 A:A36 5.0 9.3 1.0 C1' A:U33 5.0 18.7 1.0 N1 A:U33 5.0 40.4 1.0

R.S.Brown, J.C.Dewan, A.Klug. Crystallographic and Biochemical Investigation of the Lead(II)-Catalyzed Hydrolysis of Yeast Phenylalanine Trna. Biochemistry V. 24 4785 1985.
ISSN: ISSN 0006-2960
PubMed: 3907691
DOI: 10.1021/BI00339A012