Lead in PDB 1tif: Translation Initiation Factor 3 N-Terminal Domain

The structure of Translation Initiation Factor 3 N-Terminal Domain, PDB code: 1tif was solved by V.Biou, F.Shu, V.Ramakrishnan, with X-Ray Crystallography technique. A brief refinement statistics is given in the table below:

Resolution Low / High (Å)	10.00 / 1.80
Space group	P 21 21 21
Cell size a, b, c (Å), α, β, γ (°)	27.600, 39.200, 65.900, 90.00, 90.00, 90.00
R / Rfree (%)	19.2 / 23.3

The structure of Translation Initiation Factor 3 N-Terminal Domain also contains other interesting chemical elements:

Chlorine

(Cl)

2 atoms

The binding sites of Lead atom in the Translation Initiation Factor 3 N-Terminal Domain (pdb code 1tif). This binding sites where shown within 5.0 Angstroms radius around Lead atom.
In total only one binding site of Lead was determined in the Translation Initiation Factor 3 N-Terminal Domain, PDB code: 1tif:

Lead binding site 1 out of 1 in the Translation Initiation Factor 3 N-Terminal Domain


Mono view


Stereo pair view

A full contact list of Lead with other atoms in the Pb binding site number 1 of Translation Initiation Factor 3 N-Terminal Domain within 5.0Å range: probe atom residue distance (Å) B Occ A:Pb101 b:8.0 occ:0.92 PB A:PBM101 0.0 8.0 0.9 C1 A:PBM101 2.2 15.9 1.0 C3 A:PBM101 2.2 16.4 1.0 C2 A:PBM101 2.2 16.5 1.0 OE2 A:GLU36 2.6 7.8 1.0 CL A:CL102 2.9 9.3 1.1 OE1 A:GLU36 3.1 7.2 1.0 CD A:GLU36 3.2 8.3 1.0 HE22 A:GLN32 3.8 0.0 1.0 CG A:GLN32 4.5 12.6 1.0 CG A:GLU36 4.6 6.2 1.0 H2 A:HOH271 4.7 0.0 0.0 NE2 A:GLN32 4.7 15.0 1.0

V.Biou, F.Shu, V.Ramakrishnan. X-Ray Crystallography Shows That Translational Initiation Factor IF3 Consists of Two Compact Alpha/Beta Domains Linked By An Alpha-Helix. Embo J. V. 14 4056 1995.
ISSN: ISSN 0261-4189
PubMed: 7664745