Atomistry » Lead » PDB 1afv-3ec8 » 1qr7
Atomistry »
  Lead »
    PDB 1afv-3ec8 »
      1qr7 »

Lead in PDB 1qr7: Crystal Structure of Phenylalanine-Regulated 3-Deoxy-D- Arabino-Heptulosonate-7-Phosphate Synthase From Escherichia Coli Complexed with PB2+ and Pep

Enzymatic activity of Crystal Structure of Phenylalanine-Regulated 3-Deoxy-D- Arabino-Heptulosonate-7-Phosphate Synthase From Escherichia Coli Complexed with PB2+ and Pep

All present enzymatic activity of Crystal Structure of Phenylalanine-Regulated 3-Deoxy-D- Arabino-Heptulosonate-7-Phosphate Synthase From Escherichia Coli Complexed with PB2+ and Pep:
4.1.2.15;

Protein crystallography data

The structure of Crystal Structure of Phenylalanine-Regulated 3-Deoxy-D- Arabino-Heptulosonate-7-Phosphate Synthase From Escherichia Coli Complexed with PB2+ and Pep, PDB code: 1qr7 was solved by I.A.Shumilin, R.H.Kretsinger, R.H.Bauerle, with X-Ray Crystallography technique. A brief refinement statistics is given in the table below:

Resolution Low / High (Å) 18.00 / 2.60
Space group C 1 2 1
Cell size a, b, c (Å), α, β, γ (°) 211.731, 51.326, 148.099, 90.00, 116.43, 90.00
R / Rfree (%) 19.4 / 25.6

Lead Binding Sites:

The binding sites of Lead atom in the Crystal Structure of Phenylalanine-Regulated 3-Deoxy-D- Arabino-Heptulosonate-7-Phosphate Synthase From Escherichia Coli Complexed with PB2+ and Pep (pdb code 1qr7). This binding sites where shown within 5.0 Angstroms radius around Lead atom.
In total 4 binding sites of Lead where determined in the Crystal Structure of Phenylalanine-Regulated 3-Deoxy-D- Arabino-Heptulosonate-7-Phosphate Synthase From Escherichia Coli Complexed with PB2+ and Pep, PDB code: 1qr7:
Jump to Lead binding site number: 1; 2; 3; 4;

Lead binding site 1 out of 4 in 1qr7

Go back to Lead Binding Sites List in 1qr7
Lead binding site 1 out of 4 in the Crystal Structure of Phenylalanine-Regulated 3-Deoxy-D- Arabino-Heptulosonate-7-Phosphate Synthase From Escherichia Coli Complexed with PB2+ and Pep


Mono view


Stereo pair view

A full contact list of Lead with other atoms in the Pb binding site number 1 of Crystal Structure of Phenylalanine-Regulated 3-Deoxy-D- Arabino-Heptulosonate-7-Phosphate Synthase From Escherichia Coli Complexed with PB2+ and Pep within 5.0Å range:
probe atom residue distance (Å) B Occ
A:Pb351

b:41.7
occ:1.00
 NE2 A:HIS268 2.8 25.1 1.0
OD2 A:ASP326 2.9 53.1 1.0
OE2 A:GLU302 3.0 36.1 1.0
SG A:CYS61 3.2 34.6 1.0
CD2 A:HIS268 3.3 21.3 1.0
CG A:ASP326 3.4 49.5 1.0
OE1 A:GLU302 3.4 17.4 1.0
C3 A:PEP1352 3.5 24.2 1.0
CD A:GLU302 3.6 29.4 1.0
C2 A:PEP1352 3.6 37.8 1.0
O1 A:PEP1352 3.7 35.1 1.0
O A:HOH401 3.7 35.7 1.0
CB A:ASP326 3.7 41.3 1.0
C1 A:PEP1352 3.8 36.0 1.0
CE1 A:HIS268 4.0 26.7 1.0
OD1 A:ASP326 4.1 51.0 1.0
NZ A:LYS97 4.1 24.3 1.0
CB A:CYS61 4.2 31.4 1.0
O2 A:PEP1352 4.3 43.4 1.0
O2' A:PEP1352 4.5 35.9 1.0
CG A:HIS268 4.6 25.6 1.0
CE A:LYS97 4.6 5.7 1.0
NH1 A:ARG92 4.6 16.8 1.0
CA A:CYS61 4.6 33.9 1.0
NH2 A:ARG92 4.7 25.6 1.0
ND1 A:HIS268 4.9 21.0 1.0

Lead binding site 2 out of 4 in 1qr7

Go back to Lead Binding Sites List in 1qr7
Lead binding site 2 out of 4 in the Crystal Structure of Phenylalanine-Regulated 3-Deoxy-D- Arabino-Heptulosonate-7-Phosphate Synthase From Escherichia Coli Complexed with PB2+ and Pep


Mono view


Stereo pair view

A full contact list of Lead with other atoms in the Pb binding site number 2 of Crystal Structure of Phenylalanine-Regulated 3-Deoxy-D- Arabino-Heptulosonate-7-Phosphate Synthase From Escherichia Coli Complexed with PB2+ and Pep within 5.0Å range:
probe atom residue distance (Å) B Occ
B:Pb351

b:35.7
occ:1.00
 NE2 B:HIS268 2.7 17.8 1.0
OE2 B:GLU302 2.9 34.9 1.0
OD2 B:ASP326 3.0 42.8 1.0
CD2 B:HIS268 3.2 25.7 1.0
SG B:CYS61 3.3 39.4 1.0
C3 B:PEP2352 3.4 30.0 1.0
OE1 B:GLU302 3.4 33.6 1.0
CG B:ASP326 3.4 45.4 1.0
C2 B:PEP2352 3.5 28.9 1.0
CD B:GLU302 3.5 39.0 1.0
O1 B:PEP2352 3.7 39.2 1.0
O B:HOH402 3.7 28.5 1.0
C1 B:PEP2352 3.7 37.0 1.0
CB B:ASP326 3.8 40.7 1.0
CE1 B:HIS268 3.9 38.9 1.0
NZ B:LYS97 4.2 34.5 1.0
CB B:CYS61 4.2 35.9 1.0
OD1 B:ASP326 4.2 45.9 1.0
O2 B:PEP2352 4.2 32.8 1.0
O2' B:PEP2352 4.5 29.9 1.0
CG B:HIS268 4.5 31.4 1.0
NH1 B:ARG92 4.5 15.9 1.0
CE B:LYS97 4.6 24.0 1.0
CA B:CYS61 4.7 32.2 1.0
NH2 B:ARG92 4.7 20.3 1.0
ND1 B:HIS268 4.8 25.8 1.0
CG B:GLU302 5.0 35.7 1.0

Lead binding site 3 out of 4 in 1qr7

Go back to Lead Binding Sites List in 1qr7
Lead binding site 3 out of 4 in the Crystal Structure of Phenylalanine-Regulated 3-Deoxy-D- Arabino-Heptulosonate-7-Phosphate Synthase From Escherichia Coli Complexed with PB2+ and Pep


Mono view


Stereo pair view

A full contact list of Lead with other atoms in the Pb binding site number 3 of Crystal Structure of Phenylalanine-Regulated 3-Deoxy-D- Arabino-Heptulosonate-7-Phosphate Synthase From Escherichia Coli Complexed with PB2+ and Pep within 5.0Å range:
probe atom residue distance (Å) B Occ
C:Pb351

b:40.8
occ:1.00
 NE2 C:HIS268 2.8 16.6 1.0
OE2 C:GLU302 2.9 19.9 1.0
OD2 C:ASP326 3.0 43.8 1.0
CD2 C:HIS268 3.3 14.8 1.0
SG C:CYS61 3.3 13.4 1.0
CG C:ASP326 3.4 42.2 1.0
OE1 C:GLU302 3.5 23.9 1.0
C3 C:PEP3352 3.5 19.1 1.0
C2 C:PEP3352 3.6 21.0 1.0
CD C:GLU302 3.6 20.0 1.0
O C:HOH403 3.6 28.2 1.0
O1 C:PEP3352 3.8 45.7 1.0
C1 C:PEP3352 3.8 24.2 1.0
CB C:ASP326 3.8 31.1 1.0
CE1 C:HIS268 4.0 18.5 1.0
NZ C:LYS97 4.1 25.5 1.0
CB C:CYS61 4.1 17.9 1.0
OD1 C:ASP326 4.2 34.4 1.0
O2 C:PEP3352 4.3 35.1 1.0
O2' C:PEP3352 4.5 26.8 1.0
CG C:HIS268 4.6 18.8 1.0
NH1 C:ARG92 4.6 8.0 1.0
CE C:LYS97 4.6 16.0 1.0
CA C:CYS61 4.6 25.4 1.0
NH2 C:ARG92 4.7 22.0 1.0
ND1 C:HIS268 4.9 12.7 1.0

Lead binding site 4 out of 4 in 1qr7

Go back to Lead Binding Sites List in 1qr7
Lead binding site 4 out of 4 in the Crystal Structure of Phenylalanine-Regulated 3-Deoxy-D- Arabino-Heptulosonate-7-Phosphate Synthase From Escherichia Coli Complexed with PB2+ and Pep


Mono view


Stereo pair view

A full contact list of Lead with other atoms in the Pb binding site number 4 of Crystal Structure of Phenylalanine-Regulated 3-Deoxy-D- Arabino-Heptulosonate-7-Phosphate Synthase From Escherichia Coli Complexed with PB2+ and Pep within 5.0Å range:
probe atom residue distance (Å) B Occ
D:Pb351

b:42.7
occ:1.00
 NE2 D:HIS268 2.9 11.5 1.0
OE2 D:GLU302 2.9 32.2 1.0
OD2 D:ASP326 2.9 33.6 1.0
SG D:CYS61 3.2 33.7 1.0
CG D:ASP326 3.3 34.9 1.0
CD2 D:HIS268 3.4 17.1 1.0
OE1 D:GLU302 3.4 15.0 1.0
CD D:GLU302 3.5 24.1 1.0
C3 D:PEP4352 3.6 18.1 1.0
O D:HOH404 3.7 32.1 1.0
CB D:ASP326 3.7 33.9 1.0
C2 D:PEP4352 3.7 31.9 1.0
O1 D:PEP4352 3.8 38.6 1.0
C1 D:PEP4352 3.9 34.8 1.0
CE1 D:HIS268 4.0 27.7 1.0
CB D:CYS61 4.0 22.8 1.0
OD1 D:ASP326 4.1 28.9 1.0
NZ D:LYS97 4.1 23.1 1.0
O2 D:PEP4352 4.4 40.6 1.0
CE D:LYS97 4.5 18.9 1.0
CA D:CYS61 4.5 20.4 1.0
O2' D:PEP4352 4.6 38.0 1.0
NH1 D:ARG92 4.6 8.2 1.0
CG D:HIS268 4.7 15.5 1.0
NH2 D:ARG92 4.8 12.9 1.0
ND1 D:HIS268 5.0 19.3 1.0

Reference:

I.A.Shumilin, R.H.Kretsinger, R.H.Bauerle. Crystal Structure of Phenylalanine-Regulated 3-Deoxy-D-Arabino-Heptulosonate-7-Phosphate Synthase From Escherichia Coli. Structure Fold.Des. V. 7 865 1999.
ISSN: ISSN 0969-2126
PubMed: 10425687
DOI: 10.1016/S0969-2126(99)80109-9
Page generated: Thu Oct 10 10:01:59 2024

Last articles

Zn in 9J0N
Zn in 9J0O
Zn in 9J0P
Zn in 9FJX
Zn in 9EKB
Zn in 9C0F
Zn in 9CAH
Zn in 9CH0
Zn in 9CH3
Zn in 9CH1
© Copyright 2008-2020 by atomistry.com
Home   |    Site Map   |    Copyright   |    Contact us   |    Privacy