Lead in PDB 1ps1: Pentalenene Synthase

All present enzymatic activity of Pentalenene Synthase:
4.6.1.5;

The structure of Pentalenene Synthase, PDB code: 1ps1 was solved by C.A.Lesburg, D.W.Christianson, with X-Ray Crystallography technique. A brief refinement statistics is given in the table below:

Resolution Low / High (Å)	20.00 / 2.60
Space group	P 63
Cell size a, b, c (Å), α, β, γ (°)	178.720, 178.720, 56.620, 90.00, 90.00, 120.00
R / Rfree (%)	19.8 / 27.3

The binding sites of Lead atom in the Pentalenene Synthase (pdb code 1ps1). This binding sites where shown within 5.0 Angstroms radius around Lead atom.
In total only one binding site of Lead was determined in the Pentalenene Synthase, PDB code: 1ps1:

Lead binding site 1 out of 1 in the Pentalenene Synthase


Mono view


Stereo pair view

A full contact list of Lead with other atoms in the Pb binding site number 1 of Pentalenene Synthase within 5.0Å range: probe atom residue distance (Å) B Occ A:Pb500 b:71.6 occ:1.00 OE2 A:GLU89 3.2 0.3 1.0 OE1 A:GLU89 3.9 0.2 1.0 CD A:GLU89 3.9 0.2 1.0 CA A:PRO86 4.8 75.2 1.0

C.A.Lesburg, G.Zhai, D.E.Cane, D.W.Christianson. Crystal Structure of Pentalenene Synthase: Mechanistic Insights on Terpenoid Cyclization Reactions in Biology. Science V. 277 1820 1997.
ISSN: ISSN 0036-8075
PubMed: 9295272
DOI: 10.1126/SCIENCE.277.5333.1820