Lead in PDB 1fjr: Crystal Structure of the Ectodomain of Methuselah

The structure of Crystal Structure of the Ectodomain of Methuselah, PDB code: 1fjr was solved by A.P.West Jr., L.L.Llamas, P.M.Snow, S.Benzer, P.J.Bjorkman, with X-Ray Crystallography technique. A brief refinement statistics is given in the table below:

Resolution Low / High (Å)	20.00 / 2.30
Space group	P 21 21 21
Cell size a, b, c (Å), α, β, γ (°)	68.937, 73.000, 115.110, 90.00, 90.00, 90.00
R / Rfree (%)	21.2 / 22.7

The binding sites of Lead atom in the Crystal Structure of the Ectodomain of Methuselah (pdb code 1fjr). This binding sites where shown within 5.0 Angstroms radius around Lead atom.
In total 4 binding sites of Lead where determined in the Crystal Structure of the Ectodomain of Methuselah, PDB code: 1fjr:
Jump to Lead binding site number: 1; 2; 3; 4;

Lead binding site 1 out of 4 in the Crystal Structure of the Ectodomain of Methuselah


Mono view


Stereo pair view

A full contact list of Lead with other atoms in the Pb binding site number 1 of Crystal Structure of the Ectodomain of Methuselah within 5.0Å range: probe atom residue distance (Å) B Occ A:Pb602 b:48.3 occ:0.84 O A:HOH761 2.5 36.5 1.0 OD2 A:ASP139 2.7 35.0 1.0 O A:HOH830 2.8 47.6 1.0 O A:HOH715 3.1 27.6 1.0 OD1 A:ASP139 3.1 33.5 1.0 CG A:ASP139 3.2 41.3 1.0 O A:TYR131 3.9 39.0 1.0 N A:ASP133 4.6 29.0 1.0 O A:HOH878 4.7 55.6 1.0 CB A:ASP139 4.7 38.5 1.0 O A:HOH879 4.9 55.1 1.0 CA A:LEU132 4.9 32.9 1.0 CB A:ASP133 5.0 33.5 1.0

Lead binding site 2 out of 4 in the Crystal Structure of the Ectodomain of Methuselah


Mono view


Stereo pair view

A full contact list of Lead with other atoms in the Pb binding site number 2 of Crystal Structure of the Ectodomain of Methuselah within 5.0Å range: probe atom residue distance (Å) B Occ A:Pb603 b:43.0 occ:0.71 OE2 A:GLU90 2.6 35.7 1.0 O1 A:SO4402 2.9 61.3 1.0 OE1 A:GLU90 3.0 33.7 1.0 CD A:GLU90 3.1 35.7 1.0 O4 A:SO4402 3.4 65.5 1.0 S A:SO4402 3.7 64.4 1.0 O A:HOH797 3.7 43.8 1.0 O A:ASN85 4.1 30.6 1.0 O3 A:SO4402 4.2 64.4 1.0 ND2 A:ASN85 4.6 37.3 1.0 CG A:GLU90 4.6 36.1 1.0

Lead binding site 3 out of 4 in the Crystal Structure of the Ectodomain of Methuselah


Mono view


Stereo pair view

A full contact list of Lead with other atoms in the Pb binding site number 3 of Crystal Structure of the Ectodomain of Methuselah within 5.0Å range: probe atom residue distance (Å) B Occ B:Pb601 b:48.2 occ:0.90 OD2 B:ASP139 2.7 25.6 1.0 O B:HOH754 3.0 34.9 1.0 OD1 B:ASP139 3.0 23.1 1.0 O B:HOH842 3.0 50.4 1.0 CG B:ASP139 3.2 29.7 1.0 O B:TYR131 4.1 32.9 1.0 CB B:ASP139 4.7 34.5 1.0 O B:HOH779 4.7 41.1 1.0 N B:ASP133 4.8 31.8 1.0

Lead binding site 4 out of 4 in the Crystal Structure of the Ectodomain of Methuselah


Mono view


Stereo pair view

A full contact list of Lead with other atoms in the Pb binding site number 4 of Crystal Structure of the Ectodomain of Methuselah within 5.0Å range: probe atom residue distance (Å) B Occ B:Pb604 b:98.0 occ:0.57 OE1 B:GLU90 2.8 56.4 1.0 OE2 B:GLU90 2.9 57.2 1.0 CD B:GLU90 3.2 55.5 1.0 O B:HOH870 3.3 53.7 1.0 O B:ASN85 3.7 47.2 1.0 C B:ASN85 4.7 47.3 1.0 CA B:MET86 4.7 50.7 1.0 CG B:GLU90 4.8 52.7 1.0 N B:SER87 4.8 49.5 1.0 ND2 B:ASN85 5.0 47.9 1.0

A.P.West Jr., L.L.Llamas, P.M.Snow, S.Benzer, P.J.Bjorkman. Crystal Structure of the Ectodomain of Methuselah, A Drosophila G Protein-Coupled Receptor Associated with Extended Lifespan. Proc.Natl.Acad.Sci.Usa V. 98 3744 2001.
ISSN: ISSN 0027-8424
PubMed: 11274391
DOI: 10.1073/PNAS.051625298